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Recent advances in molecular cell biology have greatly expanded our understanding of the processes and mechanisms that underpin the regulation of cell replication, and what is happening at the molecular level when these fail.The third edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms that drive cancer is leading to the development of new targeted therapeutic agents.Opening with an overview of the key hallmarks of cancer as a disease state, the book then leads us through the principal processes that become altered in cancer cells, and explains how the failure of these processes can lead to the onset of cancer. 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Pecorino's book is divided into clear, self-contained chapters on various mechanisms of cancer, including genetic mutations and loss of DNA repair mechanisms, major tumor supressors such as Rb and P-53 and their roles in regulation of cell division, signaling pathways and defects in them, epigenetic mechanisms and defects, and metastasis mechanisms. LEGAL NOTICE: The following PDFs files has been found on the Web. EMBED. Download the eBook Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics - Lauren Pecorino in PDF or EPUB format and read it directly on your mobile phone, computer or any device. Get this from a library! Flag this item for. Figure 8.29 The Biology of Cancer (© Garland Science 2007) Potent mitogenic power of Myc In an experimental setting:-Myc is expressed as a fusion protein with ER. Professor Lauren Pecorino People University of Greenwich. [Lauren Pecorino] -- "The most engaging and accessible account of cancer biology that makes the link between our understanding of cancer and the development of new therapeutics crystal clear. Topics medicine Collection opensource Language English. Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers an accessible, engaging, and optimistic account of cancer biology for undergraduate and graduate students. For Just $14.00 Dollars Download this eBook and all other ebooks you want. The emphasis is not on exhaustive coverage of the field, but on acquiring a solid understanding of the essentials of the subject--and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit.The Molecular Biology of Cancer is an invaluable resource for any student wishing to gain an insight into the molecular basis of the disease--and uncover possible solutions for its effective control.COMPANION WEBSITE (www.oup.com/uk/orc/bin/9780199577170)For students:* Hyperlinks to primary literature articles featured in the text* News feeds relevant to cancer biology, drawn from a variety of publications* A web link library, giving access to relevant online resourcesFor instructors:* Downloadable figures from the book* A Test Bank of questions, with feedback linked to the book, for use in formative or summative assessment (password-protected), Molecular Biology of Cancer. 0199264724 Molecular Biology of Cancer Mechanisms. 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